Faith Osier

A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.Ogwang R, Osoti V, Wamae K, Ndwiga L, Muteru K, Ningwa A, Tuju J, Kinyanjui S, Osier F, Marsh K, Bejon P, Idro R, Ochola-Oyier LI
Antimicrob Agents Chemother, (2024). :e0157623

Full-length MSP1 is a major target of protective immunity after controlled human malaria infection.Rosenkranz M, Nkumama IN, Ogwang R, Kraker S, Blickling M, Mwai K, Odera D, Tuju J, Fürle K, Frank R, Chepsat E, Kapulu MC, Study Team CS, Osier FH
Life Sci Alliance, (2024). 7:

Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge.Nkumama IN, Ogwang R, Odera D, Musasia F, Mwai K, Nyamako L, Murungi L, Tuju J, Fürle K, Rosenkranz M, Kimathi R, Njuguna P, Hamaluba M, Kapulu MC, Frank R, Osier FHA
Immunity, (2024). 57:1215-1224

Bi-isotype immunoglobulins enhance antibody-mediated neutrophil activity against Plasmodium falciparum parasites.Ogwang R, Murugu L, Nkumama IN, Nyamako L, Kai O, Mwai K, Murungi L, Idro R, Bejon P, Tuju J, Kinyanjui SM, Osier FHA
Front Immunol, (2024). 15:1360220

Antibody-Dependent Respiratory Burst against Plasmodium falciparum Merozoites in Individuals Living in an Area with Declining Malaria Transmission.Mutemi DD, Tuju J, Ogwang R, Nyamako L, Wambui KM, Cruz IR, Villner P, Yman V, Kinyanjui SM, Rooth I, Ngasala B, Färnert A, Osier FHA
Vaccines (Basel), (2024). 12:

Characterization of a novel Plasmodium falciparum merozoite surface antigen and potential vaccine target.Niaré K, Chege T, Rosenkranz M, Mwai K, Saßmannshausen Z, Odera D, Nyamako L, Tuju J, Alfred T, Waitumbi JN, Ogutu B, Sirima SB, Awandare G, Kouriba B, Rayner JC, Osier FHA
Front Immunol, (2023). 14:1156806

Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria.Odera DO, Tuju J, Mwai K, Nkumama IN, Fürle K, Chege T, Kimathi R, Diehl S, Musasia FK, Rosenkranz M, Njuguna P, Hamaluba M, Kapulu MC, Frank R, Osier FHA, Abdi AI, Chi PC, de Laurent Z, Jao I, Kamuya D, Kamuyu G, Makale J, Murungi L, Musyoki J, Muthui M, Mwacharo J, Kariuki S, Mwanga D, Mwongeli J, Ndungu F, Njue M, Nyangweso G, Kimani D, Ngoi JM, Musembi J, Ngoto O, Otieno E, Ooko M, Shangala J, Wambua J, Mohammed KS, Omuoyo D, Mosobo M, Kibinge N, Kinyanjui S, Bejon P, Lowe B, Marsh K, Marsh V, Abebe Y, Billingsley PF, Sim BKL, Hoffman SL, James ER, Richie TL, Audi A, Olewe F, Oloo J, Ongecha J, Ongas MO, Koskei N, Bull PC, Hodgson SH, Kivisi C, Imwong M, Murphy SC, Ogutu B, Tarning J, Winterberg M, Williams TN
Sci Transl Med, (2023). 15:eabn5993

The effect of malaria on childhood anemia in a quasi-experimental study of 7,384 twins from 23 Sub-Saharan African countries.Starck T, Dambach P, Rouamba T, Tinto H, Osier F, Oldenburg CE, Adam M, Bärnighausen T, Jaenisch T, Bulstra CA
Front Public Health, (2022). 10:1009865

Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay.Fernandez N, Hayes P, Makinde J, Hare J, King D, Xu R, Rehawi O, Mezzell AT, Kato L, Mugaba S, Serwanga J, Chemweno J, Nduati E, Price MA, Osier F, Ochsenbauer C, Yue L, Hunter E, Gilmour J
Front Immunol, (2022). 13:1029029

Malaria attributable fractions with changing transmission intensity: Bayesian latent class vs logistic models.Mwai K, Nkumama I, Thairu A, Mburu J, Odera D, Kimathi R, Nyamako L, Tuju J, Kinyanjui S, Musenge E, Osier F
Malar J, (2022). 21:326

Asplenia and spleen hypofunction.Lenti MV, Luu S, Carsetti R, Osier F, Ogwang R, Nnodu OE, Wiedermann U, Spencer J, Locatelli F, Corazza GR, Di Sabatino A
Nat Rev Dis Primers, (2022). 8:71

Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria.Musasia FK, Nkumama IN, Frank R, Kipkemboi V, Schneider M, Mwai K, Odera DO, Rosenkranz M, Furle K, Kimani D, Tuju J, Njuguna P, Hamaluba M, Kapulu MC, Wardemann H, CHMI-SIKA Study Team, Osier FHA
Nat Commun, (2022). 13:4098

Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure.Yman V, Tuju J, White MT, Kamuyu G, Mwai K, Kibinge N, Asghar M, Sundling C, Sonden K, Murungi L, Kiboi D, Kimathi R, Chege T, Chepsat E, Kiyuka P, Nyamako L, Osier FHA, Farnert A
Nat Commun, (2022). 13:331

Characterization of Anopheles gambiae D7 salivary proteins as markers of human-mosquito bite contact.Oseno B, Marura F, Ogwang R, Muturi M, Njunge J, Nkumama I, Mwakesi R, Mwai K, Rono MK, Mwakubambanya R, Osier F, Tuju J
Parasit Vectors, (2022). 15:11

Malaria vaccine roller coaster.Nkumama IN, Osier FHA
Nat Microbiol, (2021). 6:1345-1346

Determinants of the varied profiles of Plasmodium falciparum infections among infants living in Kintampo, Ghana.Botwe AK, Oppong FB, Gyaase S, Owusu-Agyei S, Asghar M, Asante KP, Farnert A, Osier F
Malar J, (2021). 20:240

protGear: A protein microarray data pre-processing suite.Mwai K, Kibinge N, Tuju J, Kamuyu G, Kimathi R, Mburu J, Chepsat E, Nyamako L, Chege T, Nkumama I, Kinyanjui S, Musenge E, Osier F
Comput Struct Biotechnol J, (2021). 19:2518-2525

Correction: Profiles of Plasmodium falciparum infections detected by microscopy through the first year of life in Kintampo a high transmission area of Ghana.Botwe AK, Owusu-Agyei S, Asghar M, Hammar U, Oppong FB, Gyaase S, Dosoo D, Jakpa G, Boamah E, Twumasi MF, Osier F, Farnert A, Asante KP
PLoS One, (2021). 16:e0246773

Smashing Stereotypes: Mutual Respect, Key to Embracing Diversity.Osier FHA, Murungi LM
Trends Parasitol, (2021). 37:265-267

Turning Discoveries into Treatments: Immunology in Africa.Osier FHA, Mwandumba HC, Gray CM
Trends Immunol, (2020). 41:1051-1053